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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
42.12
Human Site:
Y769
Identified Species:
66.19
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
Y769
N
E
W
V
V
R
L
Y
Y
S
F
Q
D
K
D
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
Y769
N
E
W
V
V
R
L
Y
Y
S
F
Q
D
K
D
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
E490
Y
A
F
K
F
F
M
E
Q
H
V
E
N
V
I
Dog
Lupus familis
XP_534537
1097
121903
Y741
N
E
W
V
V
K
L
Y
Y
S
F
Q
D
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
Y768
N
E
W
V
V
R
L
Y
Y
S
F
Q
D
K
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
Y759
N
E
W
V
V
R
L
Y
Y
S
F
Q
D
K
D
Chicken
Gallus gallus
XP_419666
1136
127431
Y775
N
E
W
V
V
R
L
Y
Y
S
F
Q
D
K
D
Frog
Xenopus laevis
NP_001087838
1118
125984
Y755
N
E
W
V
V
R
L
Y
Y
S
F
Q
D
K
D
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
P726
Y
F
V
M
D
Y
I
P
G
G
D
M
M
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
Y784
N
N
W
V
V
K
L
Y
Y
S
F
Q
D
K
D
Honey Bee
Apis mellifera
XP_395146
1137
124999
Y805
N
E
W
V
V
K
L
Y
Y
S
F
Q
D
K
D
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
Y157
M
Y
Y
S
F
Q
D
Y
S
N
L
Y
L
V
M
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
Y845
N
E
W
V
V
K
L
Y
Y
S
F
Q
D
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
L437
E
F
L
P
G
G
D
L
M
T
M
L
I
R
W
Red Bread Mold
Neurospora crassa
P38679
598
67999
T279
P
W
V
V
K
L
Y
T
T
F
Q
D
A
N
F
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
0
93.3
N.A.
100
N.A.
N.A.
100
100
100
0
N.A.
86.6
93.3
6.6
93.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
N.A.
N.A.
100
100
100
13.3
N.A.
93.3
100
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
14
0
0
0
7
7
67
0
67
% D
% Glu:
7
60
0
0
0
0
0
7
0
0
0
7
0
0
0
% E
% Phe:
0
14
7
0
14
7
0
0
0
7
67
0
0
0
7
% F
% Gly:
0
0
0
0
7
7
0
0
7
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
7
% I
% Lys:
0
0
0
7
7
27
0
0
0
0
0
0
0
67
0
% K
% Leu:
0
0
7
0
0
7
67
7
0
0
7
7
7
0
7
% L
% Met:
7
0
0
7
0
0
7
0
7
0
7
7
7
0
7
% M
% Asn:
67
7
0
0
0
0
0
0
0
7
0
0
7
7
0
% N
% Pro:
7
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
7
0
7
67
0
0
0
% Q
% Arg:
0
0
0
0
0
40
0
0
0
0
0
0
0
7
0
% R
% Ser:
0
0
0
7
0
0
0
0
7
67
0
0
0
7
0
% S
% Thr:
0
0
0
0
0
0
0
7
7
7
0
0
0
0
0
% T
% Val:
0
0
14
74
67
0
0
0
0
0
7
0
0
14
0
% V
% Trp:
0
7
67
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
14
7
7
0
0
7
7
74
67
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _